PUBLICATIONS

PUBLICATIONS

 

  1. Nwagwu, M., Okenu, D.M.N., Olusi, T.A., and Molokwu R.I. (1988):Trypanosoma brucei releases proteases extracellularly. Transaction of the Royal Society of Tropical Medicine and Hygiene, Vol. 82, 577.
  2. Nwagwu, M., Inyang, A.L., Molokwu R.I., Essien, E.M. (1989): Platelet-aggregating acticity of released factor(s) from Trypanosoma Brucei.African Journal of Medicine and Medical Science,Vol. 18, 283-287.
  3. Okenu D.M.N., Opara K.N., Nwuba R.I. and Nwagwu M. (1999) Purification and Charaterisation of an extracellularly released protease ofTrypanosoma brucei. Parasitological Research, Vol. 85, 424-428. 
  4. Nwuba R. I., Anumudu, C. I., Omosun,Y.O., Sodeinde, O., and Nwagwu, M. (2001): Evaluation of a rapid immunochromatographic card test for diagnosis of Plasmodium falciparum malaria in Ibadan, Nigeria. African Journal of Medicine and medical Science, Vol.30, 230-231.
  5. Nwuba R.I., S.A. Adoro, C.I. Anumudu, A. B. Odaibo, Y. Omosun, A. Holder and M. Nwagwu (2002): Specificities of Antibodies to Plasmodium falciparum Merozoite Surface Protein (MSP-1). Proceedings of the 10thInternational congress of Parasitogy-ICOPA X: Symposia, Workshops and Contributed Papers held in Vancouver (Canada), August 4-9, 2002, 477-486. 
  6. Nwuba R. I., O. Sodeinde, C.I. Anumudu, Y. Omosun, A.B. Odaibo, A.A. Holder and Mark Nwagwu (2002): The human immune response toPlasmodium falciparum includes production of antibodies that inhibit MSP-1 secondary processing, Infection and Immunity, Vol.70, 5328-5331. Read pdf
  7. Omosun Y. O., Ayodeji O.A., Igbokwe M.C. Odaibo A.B. Nwaqwu M. andNwuba R.I. (2002): Studies of differences in the foot muscle proteins of fresh water snails: Biomphalaria Pfeifferi and Indoplanorbis exustus. The Zoologist, Vol. 1, No. 2, 47-53.
  8. Anumudu C. I., Okafor C.M.F., Ngwumohaike V., Afolabi K. A., Nwuba R. I. and M. Nwagwu (2004): Clinical manifestations and immune response to MSP119 in severe paediatric malaria in Adeoyo state maternity hospital, Ibadan. African Journal of Medicine and Medical Science, Vol. 33, 57-63.
  9. Anumudu C.I., Ukoha U., Nwuba R.I., Nwagwu M. (2004): Clinical malaria diagnosis in Adults: The value of signs, symptoms and antibodies. Journal of Medicine and Biomedical Research, Vol. 3, No. 2, 67-77.
  10. Omosun Y.O., Anumudu C.I. Adoro S., Odaibo A. B., Sodiende O., Holder A. A., Nwagwu M., Nwuba R.I. (2005): Variation in the relationship between anti-MSP-119 antibody response and age in children infected with Plasmodium falciparium during the dry and rainy seasons. Acta Tropica, Vol. 95, 233-247 (Sweden).
  11. Anumudu C. I., Adepoju A., Adediran M., Adeoye O., Kassim A., Oyewole and Nwuba R.I. (2006): Malaria Prevalence and Treatment Seeking Behaviour of Young Nigerian Adults. Annals of African Medicine, 5 (2) 82-88 (Nigeria, 30%).
  12. Anumudu C. I. , Okafor CMF, Ngwunohaike V., Afolabi K.A. Nwuba R.I.  Read pdf Nwagwu M. (2007): Epidemiological factors that promotes the development of severe malaria anaemia in children in Ibadan. African Health Sciences. 7 (2) 80-85 (Nigeria, 40%).
  13. Omosun Y.O, Anumudu CI, Adoro S, Odaibo A, Sodiende O, Holder A.A, Nwagwu M and Nwuba R.I. (2008) Anti-MSP-119 IgM Antibodies in children exposed to P. falciparum in Igbo-Ora southwestern Nigeria. Ife J. Sci. 10(1):59-65.
  14. Nwuba R. I, Omosun Y.O, Anumudu C.I, Adoro S, Odaibo A, Sodiende O, Holder A.A, and Nwagwu M. (2008) Epidemiology of malaria in children living at Igbo-Ora, south western Nigeria. Ife J. Sci. 10(1): 53-58.
  15. Omosun Y.O., Adoro S., Anumudu C. I., Odaibo A.B., Uthaipibull C., Holder A., Nwagwu M., and Nwuba R. I.(2008): Antibody specificities of children living in a malaria endemic area to inhibitory and blocking epitopes on MSP119 of Plasmodium falciparum. Acta Tropica 109 (3), 208-12.
  16. Anumudu C.I., Molehin, A, J, and Nwuba R.I. (2009): Optimization of the T-cell proliferation assay in Facioliasis using a non-radaitioactive method, the Almar Blue Assay. Nigerian Journal of Parasitology (30), 38-42.Ireiemenam N. C., Okafor C.M. F., Balogun H. A., Ayede I., Omosun Y.,
  17. Persson J., Hagstedt M., Anumudu C.I.; Nwuba R.I., Troye-blomberg M., Berzins (2009): Cytokine profiles and antibody response to Plamodium falciparum malaria infection in individuals living in Ibadan, southwest Nigeria. Afr. Health Sci. (9); 66-74. 
  18. Okafor C.M. F.; Anumudu, C.I.; Uthaipibull C.; Omosun Y. O.; Ayede I.; Awobode H.O.; Odaibo A.B.; Langhorne J.; Ho;der A.A.; Nwuba R.I.; and Troye-Bloomberg M.(2009): Cellular responses to modified Plasmodium falciparumMSP119 antigens in individuals previously exposed to natural infection. Malaria Journal (8) 263; 1-9.

 

Technical Reports:

  1. Molokwu R.I. (1991): Glycosomal phosphofructokinase of Trypanosoma(Trypanozoon) brucei brucei: Kinetics, immunology and substrate transport. Technical report on the Research work carried out under the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases.
  2. Nwuba R.I. (2002): Characteristics and Dynamics of antibodies to merozoite surface protein-1 of Plasmodium falciparum in humans naturally exposed to malaria: Cross-sectional survey of malaria prevalence, anti-MSP1 antibody titre and blood level in individuals living in Igbo-Ora. Report on the above project sponsored by Multilateral Initiative on Malaria (MIM) Research Capability Strengthening Grant for Malaria Research in Africa /TDR .. 
  3. Nwuba R.I. (2003): Characteristics and Dynamics of antibodies to merozoite surface protein-1 of Plasmodium falciparum in humans naturally exposed to malaria: The distribution of the three specific types of MSP1 antibodies (processing-inhibitory, blocking and neutral) according to age and parasitaemia. Report on the above project sponsored by Multilateral Initiative on Malaria (MIM) Research Capability Strengthening Grant for Malaria Research in Africa /TDR. 
  4. Nwuba R.I. (2004): Characteristics and Dynamics of antibodies to merozoite surface protein-1 of Plasmodium falciparum in humans naturally exposed to malaria: The dynamics of MSP119 antibody production and passive transfer from pregnant mothers to their infants from birth through the first year of life and the determination of MSP1 specific allelic families associated with the production of MSP142 processing inhibitory, blocking and neutral antibodies.. Report on the above project sponsored by Multilateral Initiative on Malaria (MIM) Research Capability Strengthening Grant for Malaria Research in Africa /TDR
  5. Nwuba R.I. (2007): Identification of markers for protective immune responses against clinical malaria using modified Plasmodium falciparummerozoite surface protein 1: The relationship between MSP142processing-inhibitory activity and invasion inhibitory activity in a malaria endemic population using the P. falciparum D10 parasite parental line and D10-PcMEGF parasite derived by allelic replacement to express the antigenically distinct MSP119 domain from P. chabaudi. Report on the above project sponsored by Multilateral Initiative on Malaria (MIM) Research Capability Strengthening Grant for Malaria Research in Africa /TDR.