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NAME:  Aderoju Amoke OSOWOLE

Academic and Professional Qualifications: B.Sc., M.Sc., Ph.D. (Chemistry) (Ibadan)

ACADEMIC TITLE:  Dr.

 

ACADEMIC STATUS:  Reader

 

Office: B17 Department of Chemistry

 

Contact (Tel): +234-809-732-7529

email:aderoju30@gmail.com 

 

Area of Specialization:

1. Medicinal Inorganic Chemistry (the use of metal chelates as chemotherapeutic agents against  various cancers, infectious diseases, essential metal

                                                              & vitamin deficiencies).

  2. Coordination and Bioinorganic Chemistry.

 

 

 Current Research Interest

  1. 1.     Syntheses, characterization, in-vitro antibacterial, antioxidant and anticancer properties of some  metal complexes of  various Schiff bases.  
  2. Synthesis, characterization, in-vivo antioxidant, antiplasmodial and analgesics properties of some metal complexes of mixed drugs.
  3. Synthesis and characterisation of metal organic frameworks.
  4. Studies on some heterocyclic ligands and their metal complexes for their potentials as biomimetics and MRI agents

 

Publications 

 

  1. Osowole, A.  A., Woods, J. A. O., Odunola, A. O. and Fagade, O. E. (2001) ‘Bactericidal activities of some metal(II) β-ketoamines and their adducts’. Nigerian Journal of Science Vol. 35(1), pp.27-35.
  2. Woods, J.  A. O., Odunola, A.O., Osowole, A. A. and Fagade O. E. (2001) ‘The effect of substitution on antimicrobial activities of some copper (II) β-ketoamines and their adducts’. Nigerian Journal of Science Vol. 35(1), pp. 21-26.
  3. Osowole, A. A., Woods, J. A. O., Odunola, A. O. and Fagade, O. E. (2001) ‘The effect of 3-chloro substitution on antimicrobial activities of some Cobalt(II) β-ketoamines and their adducts’. Bioscience Research Communications Vol. 13(4), pp. 429-433.
  4. Osowole, A. A., Woods, J. A. O. and Odunola, A. O. (2002) ‘Physicochemical properties of some nickel(II) 3-chloro β-ketoamines and their adducts with 2,2-bipyridyl and 1,10-phenanthroline’. International Journal of Chemistry Vol. 12(1), pp. 47-56.
  5. Osowole, A. A., Woods, J. A. O. and Odunola, A. O. (2002) ‘Synthesis and Characterisation of some Nickel(II) β-ketoamines and their adducts with 2,2-bipyridine and 1,10-phenanthroline’. Synth. React. Inorg. Met. Org. Chem. Vol. 32(4), pp.783-799.
  6. Osowole, A. A., Woods, J. A. O. and Odunola, A. O. (2002) ‘The effect of 2,2’-bipyridine and 1,10-phenanthroline on the antimicrobial activities of some nickel(II) β-ketoamines and nickel(II) 3-chloro β-ketoamines’. Bioscience Research Communications Vol. 14(6), pp. 531-535.

 

 

  1.  Osowole, A. A., Woods, J. A. O. and Odunola, A. O. (2003) ‘Synthesis and Physico-Chemical properties of some Copper(II) β-ketoamines and their adducts with 2,2-bipyridine and 1,10-phenanthroline.’ Synth. React. Inorg. Met. Org. Chem Vol. 33(2), pp.167-182.
  2. Woods, J. A. O., Osowole, A. A. and Odunola, A. O. (2004) ‘Synthesis and Physico-Chemical properties of some β-ketoaminato Cobalt(II) chelates and their adducts with 2,2-bipyridine and 1,10-phenanthroline’.  Synth. React. Inorg. Met. Org. Chem Vol. 34(8), pp.1471-1485.
  3. Osowole, A. A., Kolawole, G. A. and Fagade, O. E. (2004) ‘Spectroscopic Characterization and Biological Activities of the Unsymmetrical Schiff-base Nickel(II),Copper(II) and Zinc(II) Complexes and their Adducts.’ Bulletin of Science Association of Nigeria Vol. 25, pp. 57-66.
  4. Osowole, A. A., Kolawole, G. A. and Fagade, O. E. (2005) ‘Synthesis, Characterization and Antimicrobial properties of some Ni(II), Cu(II) and Zn(II) complexes of a tetradentate Schiff-base and adducts’. International Journal of Chemistry Vol. 15(4), pp.237-246. 
  5. Osowole, A. A., Kolawole, G. A. and Fagade, O. E. (2005) ‘Synthesis, Physicochemical and Biological Properties of Nickel(II), Copper(II) and Zinc(II) Complexes of an Unsymmetrical Tetradentate Schiff-base and their Adducts. Synth. React. Inorg. Met. Org. Chem and Nano-Metal Chemistry Vol.  35, pp. 829-836.
  6. Osowole, A. A and Krishnan, V (2006) ‘Optical and Electrochemical Redox Properties of Porphyrins Bearing Thianapthene Groups’. Science Focus Vol. 11(1), pp.134-138.
  7. Osowole, A. A (2006) ‘Some Copper(II) complexes of Tetradentate β-Ketoimines and Their Adducts’ Pakistan  Journal of Scientific and Industrial  Vol. 49(3),  pp. 174-180. 
  8.  Osowole, A. A. and Fagade, O. E. (2007) ‘Synthesis, characterization and  biopotency of some metal(II) β-ketoiminates and their mixed-ligand complexes’. Polish Journal of Chemistry Vol. 81,  pp. 2039-2048.
  9. Osowole, A. A., Kolawole, G. A. and Fagade, O. E. (2008) ‘Synthesis,   characterization and  Biological Studies on unsymmetrical Schiff-base Complexes of Nickel(II), Copper(II) and Zinc(II) and Adducts with  2, 2'-Dipyridyl and 1,10-phenanthroline’. J. Coord. Chem. Vol. 67(7), pp. 1046-1055.
  10. Osowole, A. A. (2008)  ‘Syntheses and Characterization of Some tetradentate Schiff-base complexes and their Heteroleptic analogs’ E-Journal of Chemistry Vol. 5(1), pp. 130-135.
  11.  Osowole, A. A. (2008) ‘ Studies on Some VO(IV), Ni(II) and Cu(II) Complexes  of Non- symmetrical Tetradentate Schiff-bases. ‘Bull. Chem. Soc. Ethiop’ Vol. 22(2), pp. 219-224.
  12.  Osowole, A.A, Ejelonu, B.C and Balogun, S.A (2008)´Spectroscopic, magnetic and anti-bacterial properties of some metal(II) unsymmetric  Schiff-base complexes and their mixed-ligand analogs ‘ Journal of Ultra  Chemistry Vol. 20(3), pp. 549-558.
  13. Kolawole, G. A. and Osowole, A. A. (2009)  ‘Synthesis and characterization of    some metal(II) complexes of isomeric unsymmetrical Schiff-bases and their adducts with  triphenylphosphine’. J. Coord. Chem Vol. 62(9), pp. 1437-1448.
  14. Osowole, A.A, . Kolawole, G. A, Kempe R and Fagade O.E (2009) ´Spectroscopic, magnetic and  biological studies on some metal(II) complexes of 3-(4,6-dimethyl-2-pyrimidinylamino)-1-phenyl-2-butenone and their adducts with 2,2´-bipyridine and 1,10-phenanthroline´. Synth. React. Inorg. Met. Org. Chem & Nano-Met.Chem. Vol. 39, pp.165-174.
  15. Osowole, A.A. (2010) ‘Synthesis, magnetic and spectral properties of some metal (II) complexes  of 2-(3-iodo-4-methyl-phenylimino)-2H-napthalene-1-one’. Journal of Ultra  Chemistry Vol. 6(1),  pp. 19-26.
  16. Osowole, A.A. (2010) ‘Synthesis, magnetic, spectral and thermal properties of some metal(II) Chromenol Schiff base’. Int. J. Chem . Vol. 20(1), pp. 21-28.
  17. Osowole A.A, Kempe R, Schobert ,  R and  Balogun S A (2010) ‘Synthesis, characterisation and in-vitro biological activities of some metal(II) complexes of 3-(-1-(4-methyl-6-chloro)-2-pyrimidinylimino)methyl-2-napthol’. Canadian Journal of Pure and Applied Science. Vol. 4(2), pp. 1169-1178.
  18. Osowole, A.A. (2011) ‘Synthesis, characterization, magnetic and thermal studies on some metal (II) thiophenyl Schiff base complexes’. International Journal of Inorganic Chemistry.  Vol. 2011, Article ID 650186, 7 pages.
  19. Osowole A.A, Kempe R, Schobert, R and  Effenberger K (2011) ‘Synthesis, spectroscopic, thermal and in-vitro anticancer properties of some m(II) complexes of 3-(-1-(4,6-dimethyl-2-pyrimidinylimino)methyl-2-napthol’. Synth. React. Inorg. Met. Org. Chem & Nano-Met.Chem. Vol. 41(7), pp. 825-833.
  20. Osowole, A. A (2011) ‘Synthesis, characterization, in-vitro antibacterial and anticancer studies on  some metal(II)  complexes of (methylsulfanyl)chromenol Schiff base’ Elixir Appl.Chem. Vol.39, pp. 4827-4831.
  21. Osowole, A. A  and  Daramola, A.O (2011) ‘Synthesis, physicochemical and Biological activities of some metal(II)  complexes of (methylsulfanyl)-2,4- benzene diol Schiff base’ Elixir Appl.Chem. Vol.39, pp. 4876-4879.
  22.  Osowole, A. A. (2011) ‘Seven Ages of Ph. D:  The age of perseverance’. Nature,Vol. 272, pp. 283-286.
  23. Osowole, A. A., Ott, I.  and Ogunlana, O. M. (2012)‘Synthesis, spectroscopic, anticancer and antimicrobial properties of some Metal(II) complexes of 2-[(2,3-dihydro-1H-inden-4-ylimino) methyl]-5-nitrophenol’. International Journal of  Inorganic Chemistry, Vol.  2012, Article ID 206417, 6 pages.
  24. Osowole, A. A. and  Balogun S.A.(2012) ‘Spectral, magnetic, thermal and anti-bacterial studies on some metal(II) complexes of aminoindanyl Schiff  base’. European Journal of Applied Sciences, Vol. 4(1), pp. 6-13.
  25. Osowole, A. A. and Akpan, E. J. (2012) ’Synthesis, spectroscopic characterisation,   in-vitro anticancer and antimicrobial  and  properties of  some metal(II) complexes of 3-{4,6- dimethoxypyrimidinyl)imino methyl} naphthalen-2-ol’. European Journal of Applied Sciences, Vol. 4(1), pp. 14-20.
  26. Osowole, A. A.  and Daramola,  A. O. (2012) ‘Synthesis, spectroscopic characterization and in-vitro antibacterial properties of some metal(II) complexes of Schiff bases containing aminoindane moiety’. Elixir Applied Chemistry, Vol. 47,   pp. 8662- 8666.
  27. Osowole, A. A. (2012) ’Synthesis, Spectroscopic characterization, in-vitro antibacterial and antiproliferative activities of some metal(II)  complexes of 3, 4- dihydronaphthalen-1(2H)-one Schiff base’. Excli, Vol. 11, pp. 338-345.
  28. Osowole,  A. A.   (2012) ‘Synthesis, physicochemical and in-vitro anti-bacterial  properties of some novel metal(II) complexes of 3-{[(6-methoxypyridin-3-yl)imino]methyl} aphthalene-2-ol’. Elixir Applied Chemistry, Vol. 48, pp. 9325-9328.
  29. Osowole, A. A, Kempe, R. and  Schobert,  R. (2012) ‘Synthesis, spectral, thermal, in-vitro antibacterial and anticancer activities of some metal(II) complexes of 3-(-1,4-methoxy-6-methyl-2-pyrimidinylimino)methyl-2-napthol’. International Research Journal of Pure and Applied Chemistry, Vol. 2(2), pp. 105-129.  
  30. Osowole,  A. A and  Ott, I. (2012) ‘Synthesis, characterization, in-vitro anticancer and  antimicrobial properties of some metal(II) complexes of 4-[(2,3-dihydro-1H- inden-4-ylimino) methyl] benzene-2, 4-diol’. International Research Journal of Pure and Applied Chemistry, Vol. 2(2), pp. 156-169.
  31. Osowole, A. A,  Oni, A. A, Onyegbula, K and Hassan, A. T (2012) ‘Synthesis, spectral, magnetic and in-vitro anticancer properties of some Metal(II) complexes of 3-[2,4-dihydro-1H-inden-4-ylimino) methyl] napthalen-2-ol’. International Research Journal of Pure and Applied Chemistry, Vol. 2(3), pp. 211-220
  32. Osowole, A. A, Oni, A. A, Onyegbula, K and Hassan, A. T (2013) ‘Effects of Injected N-Methyl-N-Nitrosourea (MNU) in Albino Mice on the Histology and Haematology of Selected Organs of the Circulatory, Lymphoid and Digestive Systems’. British Journal of Applied Science & Technology, Vol. 3(1), pp. 17-33.
  33. Osowole, A. A and Olarenwaju O. A. (2013) ‘Synthesis, physicochemical and in- vitro antibacterial properties of some novel metal (II) complexes of 3-{[(6-methoxypyridin-3-yl)imino]methyl}-5-nitrophenol’. Elixir Appl. Chem., Vol. 54, pp. 12285-12288.
  34. Osowole, A. A and Festus, C (2013) ’Synthesis, characterisation and antibacterial  activities of some  metal(II) complexes of 3-(-1-(2-pyrimidinylimino)methyl-2-napthol’. Elixir Appl. Chem., Vol.59, pp. 15843-15847.
  35. Osowole, A. A, Ekennia, A.C, Achugbu, B. O and Etuk, G. H (2013)’Synthesis, spectroscopic characterisation and structure related antibacterial activities of some metal(II) complexes of substituted triflurobutenol’. Elixir Appl.Chem., Vol. 59, pp. 15848-15852.

42.  Osowole, A. A, Ekenia, A. C and Achugbu, B. O.(2013) ‘Synthesis, Spectroscopic

Characterization and antibacterial Properties of some Metal (II) Complexes of 2-(6-methoxybenzothiazol-2-ylimino)methyl)-4-nitrophenol’. Research & Reviews: Journal of Pharmaceutical Analysis, Vol. 2(2), pp. 1-5.

      43. Osowole, A. A  and Oni, T. I. (2013) ‘Synthesis, spectroscopic characterization and  

            antibacterial activities of mixed ligand metal(II) complexes of 4-amino-6-chloro-2-

            methyl thio pyrimidine and 1,10-phenanthroline’. Scientific Research Reports. Vol.

             1(1), pp.  25-31.

      44. Osowole, A. A  and  Oni, T. I. (2013) ‘Synthesis, characterization and antibacterial

activities of some metal(II) complexes of 4-amino-2,6-dichloropyrimidine’. Scientific Research Reports, Vol. 1(1), 32-37.

      45. Osowole, A. A and Yoade, R.O. (2013) ‘Synthesis, characterization and

antibacterial studies on some metal(II) complexes of 4-amino-6-hydroxy-2- mercapto pyrimidine’. Scientific Journal of Applied Research, Vol.1(4), 95-100.

46. Osowole, A. A and Yoade, R.O. (2013)‘Synthesis, characterization and biopotency

of some mixed ligand metal(II) complexes of 4-amino-6-hydroxy-2-mercapto pyrimidine and 2,2’-bipyridine’. Scientific Journal of Applied Research, Vol.1(4), 101-106.

47. Osowole, A.A and Ekennia, A.C (2013) ‘Synthesis, spectroscopic characterization

and in-vitro antibacterial properties of some metal(II) complexes of 4-nitro-6-[(4-thiophen-3-yl-phenylimino)-methyl]-phenol’. Centre Point Journal(science edition), Vol. 19(1), pp.1-10.  

      48. Osowole, A. A and Ekennia, A. C (2013) ‘Some Metal(II) complexes of {2-methy-1-

             phenyl-3-(p-toluimino)-1-propenol} and their heteroleptic analogues’. Centre Point 

            Journal (science edition), Vol. 19(2), pp.161-168.  

49. Osowole, A.A, Oni A.A and Hassan A. T( 2013) ‘Effects of MNU in Albino Mice on

      Histology of Selected Organs; Effects of a standard carcinogen in Swiss albino mice’.   

      Lap Lambert Academic Publishing, pp. 1-157

50. Osowole, A.A, Agbaje O. B. A and Ojo, B.O( 2014) ‘Synthesis, characterization and

antibacterial properties of some heteroleptic metal(II) complexes of Paracetamol and Vanillin’. Asian J Pharm  Clin Res., Vol. 7(3), pp.145-149

 51. Osowole, A. A, Ekennia, A. C  and Osukwe, A. E (2014) ‘Synthesis, Spectroscopic

       and Antibacterial Properties of Some Metal(II) Mixed Ligand Complexes of Riboflavin    

       and 2,2’-Bipyridine’. Research and Reviews:Journal of Chemistry, Vol.3(1),pp.32-37.

      52. Ekennia, A. C, Onwudiwe, D. C and Osowole, A. A (2014) ‘Synthesis, Spectral,

      thermal stability and antibacterial studies of copper, nickel and cobalt complexes of  

      N-methyl-N-phenyl dithiocarbamate’. J.Sulfur Chemistry, Vol. 36(1), pp. 96-104.

      53. Osowole, A. A, Wakil, S. M  and Malumi, O. E (2015) ‘Synthesis, Characterization,

      Antioxidant and Antimicrobial activities of Some Metal(II) Complexes of  the Mixed- 

      Ligands, Vitamin B2 and Benzoic acid’. Elixir Appl. Chem., Vol. 79, pp. 30370-30374.

 54. Osowole, A. A., Wakil, S. M and Okediran, E. Q (2015) ‘Synthesis, characterization

and antimicrobial activities of some Metal(II) complexes of mixed ligands-dimethyl dithiocarbamic and para aminobenzoic acids’. Elixir Appl. Chem., Vol.79, pp. 30375-30378.

55. Agbaje. O. B. A., Osowole, A .A, Malumi, E.O and Wakil,S. M (2015)‘Synthesis,

spectroscopic characterization, antimicrobial and antioxidant properties of some metal(II) complexes of mixed ligands-Riboflavin and 4-aminobenzoic acid’. Research and Reviews: Journal of Chemistry, Vol. 4(1), pp. 1-7.

56. Osowole, A .A, Agbaje, O. B. A.  and Wakil,S. M (2015)‘Synthesis, characterization  and

biological activity of some mixed metal(II) complexes of Paracetamol and Benzoic  acid’. International Journal of Applied  Medical Sciences, Vol. 1(2) , pp. 77-87.

57. Osowole A. A, Malumi, E. O, Wakil, S. M and Alao,O. K(2015) ‘Synthesis,

characterization, antioxidant and antimicrobial activities of some mixed-drug metal(II) complexes of Vitamins B2 and B3’. International Journal of Applied Medical Sciences, Vol. 1(2), pp. 88-97.

58. Osowole A. A, Wakil, S. M and Alao,O. K (2015) ‘Synthesis, characterization and

antimicrobial activity of some mixed Trimethoprim-Sulfamethoxazole metal drug complexes’. World Applied Sciences Journal, Vol. 3(2), pp. 336-342.

59. Osowole, A. A, Malumi, E. O and Odutemu, A. E (2015)‘Synthesis, Magnetic, Spectral

and Antioxidant Properties of Some Metal(II) Mixed-Drug Complexes of Aspirin and Vitamin B3’. Research and Reviews: Journal of Chemistry, Vol. 4(1), pp.  60-65.

60. Osowole, A. A and Festus C (2015)‘Synthesis, characterization, antibacterial and

antioxidant activities of some heteroleptic Metal(II) complexes of 3-{[-pyrimidin-2-yl) imino]methyl}napthalen-2-ol’. J. Chem. Bio. Phy. Sci. Sec. A., Vol. 6(1), pp.   80-89.

61. Osowole, A. A and Festus C (2015) ‘Synthesis, spectral and antibacterial studies of

      some metal(II) complexes of  3-{[(4,6-dihydroxy pyrimidin-2-yl)Imino]methyl} Napthalen-

      2-ol’. J. Chem. Bio. Phy. Sci. Sec. A, Vol. 6(1), pp.  210-219

62. Ekennia,  A. C,  Onwudiwe, D.C, Olasunkanmi, L.O, Osowole, A. A and  Ebenso, E. E

(2015)‘Synthesis, dft calculation and antimicrobial studies of novel Zn(II), Co(II), Cu(II) and Mn(II) heteroleptic complexes containing benzoylacetone and dithiocarbamate’. Bioinorganic Chemistry  and Applications, Vol. 2015, Article ID 789063, 12 pages.

63. Osowole, A. A, Oni, A. A, Popoola P. O, Onyegbula, K. and Hassan, A. T (2016) ‘The

Antitumor Properties of a Metal-free Ligand and Local Herbal Remedy against N-methyl-Nnitrosourea (MNU)-induced Carcinomas in Albino Mice’. British Journal of Pharmaceutical Research, Vol. 10(1),  pp.1-17.

64. Osowole, A. A , Wakil, S.M, Okediran, E. Q and Alao, O.K (2016) ‘Synthesis,

Spectroscopic and Antimicrobial Properties of Some Metal (II) Complexes of Mixed Ligands-Nicotinic and N, N’-Dimethyldithiocarbamic Acids’. Chemistry Journal(UK), Vol. 6(1), pp. 22-26.

65. Osowole, A. A , Wakil, S.M, Okediran, E. Q and Alao, O.K (2016) ‘Studies on  some

Metal(II) Complexes of Mixed Ligands-Benzoic and N, N’- Dimethyldithiocarbamic  acids’. Chemistry Journal(UK), Vol. 6(1), pp. 27-31.

66. Ekennia,  A. C,  Onwudiwe, D.C, Osowole, A. A, Olasunkanmi, L.O, and  Ebenso E. E

      (2016) ‘Synthesis, biological, and quantum chemical studies of Zn(II) and Ni(II) mixed

      ligand complexes derived from N,N’-disubstituted dithiocarbamate and benzoic acid’.

     Journal of Chemistry, Vol. 2016, Article ID 5129010, 12 pages.

 

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